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ChemicalBook--->CAS DataBase List--->59721-28-7

59721-28-7

59721-28-7 Structure

59721-28-7 Structure
IdentificationBack Directory
[Name]

Camostat
[CAS]

59721-28-7
[Synonyms]

FOY 305
CAMOSTAT
Camostatum
Ccris 7219
FOY-305:Foipan
Unii-0fd207wkdu
Camostatum [inn-latin]
Camostat Monomethanesulfonate
59721-29-8 (Monomethanesulfonate)
Camostat (base and/or unspecified salts)
Dimethylcarbamoylmethyl 4-(4-guqnidinobenzoyloxy)phenylacetat
N,N-Dimethylcarbamoylmethyl-p(p-guanidinobenzoyloxy)phenylacetate
2-(Dimethylamino)-2-oxoethyl 4-(4-guanidinobenzoyloxy)phenylacetate
p-(p-Guanidinobenzoyloxy)phenylacetic acid=dimethylcarbamoylmethyl ester
4-Guanidinobenzoic acid-4-(dimethylcarbamoylmethoxycarbonylmethyl)phenyl ester
2-{4-[(4-carbaMiMidaMidophenyl)carbonyloxy]phenyl}-3-(diMethylcarbaMoyl)propanoate
4-Guanidinobenzoic acid 4-[[[(dimethylcarbamoyl)methoxy]carbonyl]methyl]phenyl ester
4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneaxetic acid 2-(dimethylamino)-oxoethyl ester
4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneacetic acid 2-(dimethylamino)-2-oxoethyl ester
Benzeneacetic acid, 4-[[4-[(aMinoiMinoMethyl)aMino]benzoyl]oxy]-, 2-(diMethylaMino)-2-oxoethyl ester
4-[[4-[(aMinoiMinoMethyl)aMino]benzoyl]oxy]-, 2-(diMethylaMino)-2-oxoethyl ester, MonoMethanesulfonate
[Molecular Formula]

C20H22N4O5
[MDL Number]

MFCD00867896
[MOL File]

59721-28-7.mol
[Molecular Weight]

398.41
Chemical PropertiesBack Directory
[Boiling point ]

590.5±60.0 °C(Predicted)
[density ]

1.28±0.1 g/cm3(Predicted)
[pka]

10.17±0.10(Predicted)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Triethylamine-->Methyl bromide-->4-Hydroxyphenylacetic acid-->2-BROMOACETAMIDE
Hazard InformationBack Directory
[Definition]

ChEBI: Camostat is a benzoate ester resulting from the formal condensation of the carboxy group of 4-guanidinobenzoic acid with the hydroxy group of 2-(dimethylamino)-2-oxoethyl (4-hydroxyphenyl)acetate. It is a potent inhibitor of the human transmembrane protease serine 2 (TMPRSS2) and its mesylate salt is currently under investigation for its effectiveness in COVID-19 patients. It has a role as an anticoronaviral agent, a serine protease inhibitor, an antifibrinolytic drug, an anti-inflammatory agent, an antiviral agent, an antihypertensive agent and an antineoplastic agent. It is a tertiary carboxamide, a carboxylic ester, a diester, a member of guanidines and a benzoate ester. It is functionally related to a 4-guanidinobenzoic acid. It is a conjugate base of a camostat(1+).
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