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ChemicalBook--->CAS DataBase List--->571190-22-2

571190-22-2

571190-22-2 Structure

571190-22-2 Structure
IdentificationBack Directory
[Name]

Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]-
[CAS]

571190-22-2
[Synonyms]

Palbociclib-1
Palbociclib-010
6-Desacetyl Palbociclib
8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)a...
8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
8-Cyclopentyl-5-methyl-2-[[(5-piperazin-1-ylpyridin-2-yl)]amino]-8H-pyrido[2,3-d]pyrimidin-7-one
8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]- Pyrido[2,3-d]pyrimidin-7(8H)-one
Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]-
Palbociclib impurity 12/8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
[Molecular Formula]

C22H27N7O
[MOL File]

571190-22-2.mol
[Molecular Weight]

405.5
Chemical PropertiesBack Directory
[Melting point ]

>200oC (dec.)
[Boiling point ]

651.3±65.0 °C(Predicted)
[density ]

1.301±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C, Inert atmosphere
[solubility ]

Acetonitrile (Slightly), Chloroform (Slightly)
[form ]

Solid
[pka]

8.66±0.10(Predicted)
[color ]

Light Yellow
Hazard InformationBack Directory
[Uses]

6-Desacetyl Palbociclib is an impurity of Palbociclib (P139900),(also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.
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