| Identification | Back Directory | [Name]
4-(2-AMINO-ETHYL)-2-METHOXY-PHENOL
| [CAS]
554-52-9 | [Synonyms]
Methoxytyramine
3-Methyldopamine
Homovanily amine
3-Methoxydopamine
4-(2-Aminoeth-yl)guaiacol
4-(2-Aminoethyl)-2-methoxyphenol
3-Methoxy-4-hydroxyphenethylamine
4-HYDROXY-3-METHOXYPHENETHYLAMINE
4-(2-Aminoethyl)-2-methoxyphenol ,98%
4-(2-AMino-ethyl)-2-Methoxy-phenol.HCl | [EINECS(EC#)]
205-525-8 | [Molecular Formula]
C9H13NO2 | [MDL Number]
MFCD00060621 | [MOL File]
554-52-9.mol | [Molecular Weight]
167.2 |
| Chemical Properties | Back Directory | [Melting point ]
89 °C | [Boiling point ]
304.5±27.0 °C(Predicted) | [density ]
1.126±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator, under inert atmosphere | [solubility ]
Acetonitrile (Slightly, Heated), Methanol (Slightly, Heated), Water (Slightly) | [form ]
Solid | [pka]
9.57±0.31(Predicted) | [color ]
Pale Brown to Light Brown | [Stability:]
Hygroscopic | [NIST Chemistry Reference]
3-Methoxy-4-hydroxyphenylethyl amine(554-52-9) |
| Hazard Information | Back Directory | [Chemical Properties]
Grey crystalline powder | [Uses]
4-?(2-?Aminoethyl)?-?2-?methoxyphenol is a respective metabolite to dopamine and is being biologically study in Parkinson’s disease, and Wilms’ tumors. | [Definition]
ChEBI: 3-methoxytyramine is a monomethoxybenzene that is dopamine in which the hydroxy group at position 3 is replaced by a methoxy group. It is a metabolite of the neurotransmitter dopamine and considered a potential biomarker of pheochromocytomas and paragangliomas. It has a role as a human blood serum metabolite, a human urinary metabolite and a biomarker. It is a member of phenols, a primary amino compound, a monomethoxybenzene and a phenylethylamine. It is functionally related to a dopamine. It is a conjugate base of a 3-methoxytyraminium. | [in vivo]
The extracellular dopamine (DA) metabolite 3-methoxytyramine (3-MT) induces significant behavioral activation in dopamine-deficient DAT-KO (DDD) mice. 3-Methoxytyramine induces behavioral activation and intracellular signaling in the striatum of DA deficient mice[1]. | [IC 50]
Human Endogenous Metabolite |
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