| Identification | Back Directory | [Name]
Impromidine | [CAS]
55273-05-7 | [Synonyms]
SKF-92676
Impromidine
Impromidina
Impromidinum
1-[3-(1H-Imidazol-4-yl)propyl]-3-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]guanidine
Guanidine, N-[3-(1H-imidazol-5-yl)propyl]-N'-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]- | [Molecular Formula]
C14H23N7S | [MDL Number]
MFCD00867262 | [MOL File]
55273-05-7.mol | [Molecular Weight]
321.44 |
| Hazard Information | Back Directory | [Uses]
Impromidine (SKF 92676) is a potent agonist for histamine H2 receptor. Impromidine induces gastric mucosal blood flow and acid secretion[1][2]. | [IC 50]
H2 Receptor | [References]
[1] Durant GJ, et al. Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors. Nature. 1978 Nov 23;276(5686):403-5. DOI:10.1038/276403a0
[2] McIsaac RL, et al. Gastric mucosal blood flow and acid secretory changes in man with impromidine: a new specific histamine-H2-receptor agonist. Gut. 1981 Jul;22(7):529-33. DOI:10.1136/gut.22.7.529 |
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