| Identification | Back Directory | [Name]
(-)-BICUCULLINE METHOCHLORIDE | [CAS]
53552-05-9 | [Synonyms]
l-Bicuculline methochloride
(-)-BICUCULLINE METHOCHLORIDE
(?)-Bicuculline methochloride
[R-(R,S)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium chloride
[R-(R*,S*)]-5-(6,8-DIHYDRO-8-OXOFURO[3,4-E]-1,3-BENZODIOXOL-6-YL)-5,6,7,8-TETRAHYDRO-6,6-DIMETHYL-1,3-DIOXOLO[4,5-G]ISOQUINOLINIUM CHLORIDE
1,3-Dioxolo[4,5-g]isoquinolinium,5-[(6S)-6,8-dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-,chloride (1:1), (5R)- | [Molecular Formula]
C21H20ClNO6 | [MDL Number]
MFCD00078981 | [MOL File]
53552-05-9.mol | [Molecular Weight]
417.84 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at RT | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml | [form ]
Powder | [Water Solubility ]
Soluble to 100 mM in water |
| Hazard Information | Back Directory | [Uses]
(-)-Bicuculline Methochloride is a GABA receptor inhibitor. Convulsant. | [Biological Activity]
Methochloride salt of (+)-bicuculline ([R-(R*,S*)]-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)furo[3,4-e]-1,3-benzodioxol-8(6H)-one ). Water soluble and more stable than bicuculline. Non-GABA receptor-mediated actions reported. | [target]
GABA Receptor |
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