| Identification | Back Directory | [Name]
(+)-SYLVATESMIN | [CAS]
487-39-8 | [Synonyms]
Philligenin
Phillygenin
Phillygenol
phylligenin
Forsythigenol
(+)-Sylvatesmin
(+)-Phillygenin
Phillygenin, >98%
Phillygenin (Phillygenol
(+)-SYLVATESMIN USP/EP/BP
Epipinoresinol methyl ether
4-[(1S,3aR,4R,6aR)-4-(3,4-Dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenol
Phenol,4-[(1S,3aR,4R,6aR)-4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxy-
(1S,3aβ,6aβ)-1β-(3-Methoxy-4-hydroxyphenyl)-4α-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan
4-[[(1S)-4α-(3,4-Dimethoxyphenyl)-3aβ,4,6,6aβ-tetrahydro-1H,3H-furo[3,4-c]furan]-1β-yl]-2-methoxyphenol
4-[(3S,3aR,6R,6aR)-6-(3,4-dimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenol
(1S)-1β-(3-Methoxy-4-hydroxyphenyl)-4α-(3,4-dimethoxyphenyl)-3aβ,4,6,6aβ-tetrahydro-1H,3H-furo[3,4-c]furan
Phenol, 4-(4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo(3,4-C)furan-1-yl)-2-methoxy-, (1S-(1alpha,3aalpha,4beta,6aalpha))- | [Molecular Formula]
C21H24O6 | [MDL Number]
MFCD01075148 | [MOL File]
487-39-8.mol | [Molecular Weight]
372.41 |
| Chemical Properties | Back Directory | [Melting point ]
133℃ | [Boiling point ]
534.9±50.0 °C(Predicted) | [density ]
1.225 | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:5): 0.16 mg/ml | [form ]
A crystalline solid | [pka]
9.84±0.35(Predicted) | [color ]
White to off-white | [LogP]
2.034 (est) |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Forsythia. | [Uses]
(+)-Sylvatesmin is a useful research chemical compound found ias a lignan of forysthia intermedia. | [Biological Activity]
Phillygenin is an active component of Forsythia, which has many medicinal values, such as antioxidants, lowering blood lipids, and inhibiting low-density lipoprotein oxidation. | [in vitro]
1) Phillygenin shows a greater inhibition on mouse B16 melanoma cells potential than vincristine.
2) phillygenin had notable scavenging activity against DPPH, ABTS radicals, as well as potent reducing power in FRAP assay. < /p> | [in vivo]
The reference for rat is 5.6 mg/ml ( iv). |
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