| Identification | Back Directory | [Name]
FRAXINOL | [CAS]
486-28-2 | [Synonyms]
Fraxil
FRAXINOL
5,7-Dimethoxy-6-hydroxycoumarin
6-Hydroxy-5,7-dimethoxycoumarin
6-Hydroxy-5,7-dimethoxy-chromen-2-one
6-Hydroxy-5,7-dimethoxy-2H-1-benzopyran-2-one | [Molecular Formula]
C11H10O5 | [MDL Number]
MFCD08693526 | [MOL File]
486-28-2.mol | [Molecular Weight]
222.19 |
| Chemical Properties | Back Directory | [Melting point ]
170-172℃ | [Boiling point ]
449.7±45.0 °C(Predicted) | [density ]
1.358 | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO and methanol; | [form ]
powder | [pka]
8.95±0.20(Predicted) | [color ]
White-yellowish | [Water Solubility ]
slightly soluble in water | [CAS DataBase Reference]
486-28-2 |
| Hazard Information | Back Directory | [Description]
Fraxinol is a coumarin originally isolated from Ash tree bark.1 It inhibits growth of GLC-4 small cell lung carcinoma and COLO 320 colorectal cancer cells (IC50s = 193 and 165 μM, respectively).2 Fraxinol potentiates barbiturate-induced sleep in rats and rabbits.3 |
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