| Identification | Back Directory | [Name]
RK-20448 | [CAS]
479501-40-1 | [Synonyms]
RK-20448
RK20449 HCK inhibitor (Cis)
RK20449 HCK inhibitor (Trans)
7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-[cis-4-(4-methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl)- | [Molecular Formula]
C29H34N6O | [MDL Number]
MFCD31615458 | [MOL File]
479501-40-1.mol | [Molecular Weight]
482.62 |
| Hazard Information | Back Directory | [Uses]
RK 20448-Trihydrochloride is a relative of A 419259 Trihydrochloride (A101040), which is the hydrochloride form of A 419259, a Src kinase inhibitor and can be used in treatment of chronic myelogenous leukemia, lymphangioleiomyomatosis and tuberous sclerosis. | [IC 50]
Lck: 0.24 μM (IC50); Blk: 0.37 μM (IC50); Fyn: 2.03 μM (IC50); Tie2: 5.85 μM (IC50); VEGFR2: 10.74 μM (IC50) |
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| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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