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ChemicalBook--->CAS DataBase List--->4429-63-4

4429-63-4

4429-63-4 Structure

4429-63-4 Structure
IdentificationBack Directory
[Name]

TABERSONINE
[CAS]

4429-63-4
[Synonyms]

C09244
tabersonin
abersonine
TABERSONINE
TABERSONINE(SH)
,12-beta,19-alpha)-
Tabersonine 4429-63-4
Hydrochloric acid it Boning
Tabersonine, 98%, from Voacanga africana Staph.
Tabersonine Hydrochloride,from Vocanga Africana
TABERSONINE HYDROCHLORIDE FROM VOCANGA AFRICANA 98%
Methyl (5α,12β,19α)-2,3,6,7-tetradehydroaspidospermidine-3-carboxylate
aspidospermidine-3-carboxylicacid,2,3,6,7-tetrahydro-,methylester,(5-alpha
(5α,12β,19α)-2,3,6,7-Tetrahydro-aspidospermidine-3-carboxylic acid methyl ester
(5α,12R,19α)-2,3,6,7-TetradehydroaspidosperMidine-3-carboxylic Acid Methyl Ester
AspidosperMidine-3-carboxylicacid, 2,3,6,7-tetradehydro-, Methyl ester, (5a,12R,19a)-
Aspidospermidine-3-carboxylic acid, 2,3,6,7-tetradehydro-, methyl ester, (5α,12R,19α)-
3a-Ethyl-3a,4,6,11,12,13a-hexahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylic Acid Methyl Ester
Aspidospermidine-3-carboxylic acid, 2,3,6,7-tetradehydro-, methyl ester, (5alpha,12beta,19alpha)-
[EINECS(EC#)]

224-615-0
[Molecular Formula]

C21H24N2O2
[MDL Number]

MFCD01632757
[MOL File]

4429-63-4.mol
[Molecular Weight]

336.43
Chemical PropertiesBack Directory
[Occurrence]

The seeds of Amsonia elliptica contain this N-oxide at tabersonine.
[Melting point ]

196 °C
[Boiling point ]

488.7±45.0 °C(Predicted)
[density ]

1.27±0.1 g/cm3(Predicted)
[storage temp. ]

Inert atmosphere,Store in freezer, under -20°C
[solubility ]

Chloroform (Slightly), Ethanol (Slightly, Sonicated), Ethyl Acetate (Slightly)
[form ]

Solid
[pka]

7?+-.0.60(Predicted)
[color ]

Light Yellow to Dark Yellow
[Stability:]

Light Sensitive
Hazard InformationBack Directory
[Chemical Properties]

Dark Yellow Low Melting Solid
[Uses]

(-)-Tabersonine is one of the terpenoid indole alkaloids (TIAs) from Catharanthus roseus. (-)-Tabersonine shows hypotensive activity, anti-tumor activity, hypoglycemic, diuretic activity.
[Definition]

ChEBI: A monoterpenoid indole alkaloid with cytotoxic activity.
[Description]

This alkaloid, found in Amsonia tabernaemontana, is difficult to obtain crystalline but the hydrochloride is readily crystallizable and has m.p. 195-6°C; [α]D - 310° (c 0.134, MeOH).
[References]

lanot, Paourrat, LeMen., Bull. Soc. Chim. Fr., 707 (1954)
Plat et al., Tetrahedron Lett., 271 (1962)
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