| Identification | Back Directory | [Name]
2-Heptylquinoline-4(1H)-one | [CAS]
40522-46-1 | [Synonyms]
Pseudane VII
Dihydroakutine
2-Heptyl-4-quinolone
2-Heptylquinolin-4(1H)-one
2-heptyl-1H-quinolin-4-one
2-Heptyl-4(1H)-quinolinone
2-Heptylquinoline-4(1H)-one
4(1H)-Quinolinone, 2-heptyl- | [Molecular Formula]
C16H21NO | [MDL Number]
MFCD16619170 | [MOL File]
40522-46-1.mol | [Molecular Weight]
243.34 |
| Chemical Properties | Back Directory | [Melting point ]
122-126 °C | [Boiling point ]
361.5±42.0 °C(Predicted) | [density ]
1.013 | [storage temp. ]
2-8°C | [solubility ]
DMSO: soluble5mg/mL, clear | [form ]
powder | [pka]
2.34±0.70(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Uses]
2-Heptyl-4-quinolone is an intermediate in the synthesis of the Pseudomonas quinolone signal (PQS) that controls swarming by positively regulating phenazine production. 2-Heptyl-4-quinolone induces the production of the phenazine-1-carboxylic acid (PCA)[1]. | [Definition]
ChEBI: A quinolone consisting of quinolin-4(1H)-one carrying a heptyl substituent at position 2. | [General Description]
HHQ belongs to 2-alkyl-4-quinolone compounds, which are lipophilic and are slightly soluble in water. | [Biochem/physiol Actions]
HHQ stimulates vesicle formation but not as much as PQS. | [References]
[1] Ha DG, et al. 2-Heptyl-4-quinolone, a precursor of the Pseudomonas quinolone signal molecule, modulates swarming motility in Pseudomonas aeruginosa. J Bacteriol. 2011 Dec;193(23):6770-80. DOI:10.1128/JB.05929-11 |
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