| Identification | Back Directory | [Name]
1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine | [CAS]
393845-24-4 | [Synonyms]
VU0080241
1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine | [Molecular Formula]
C19H23N5 | [MDL Number]
MFCD03474901 | [MOL File]
393845-24-4.mol | [Molecular Weight]
321.42 |
| Chemical Properties | Back Directory | [Boiling point ]
447.5±45.0 °C(Predicted) | [density ]
1.24±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
4.83±0.30(Predicted) | [color ]
Yellow to orange |
| Hazard Information | Back Directory | [Description]
VU0080241 is a positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4). | [Uses]
VU0080241 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 4 (mGluR4), with an EC50 of 4.6 μM[1]. | [IC 50]
mGlu4: 4.6 μM (EC50) | [References]
[1] Colleen M Niswender, et al. Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4): Part I. Discovery of pyrazolo[3,4-d]pyrimidines as novel mGluR4 positive allosteric modulators. Bioorg Med Chem Lett. 2008 Oct 15; 18(20) DOI:10.1016/j.bmcl.2008.08.087 |
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| Company Name: |
PHARMEKS Ltd.
|
| Tel: |
+7 (495) 702-9648 |
| Website: |
www.pharmeks.com |
| Company Name: |
OTAVA chemicals
|
| Tel: |
416 305 9979 (Canada) |
| Website: |
www.otavachemicals.com |
|