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ChemicalBook--->CAS DataBase List--->393845-24-4

393845-24-4

393845-24-4 Structure

393845-24-4 Structure
IdentificationBack Directory
[Name]

1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine
[CAS]

393845-24-4
[Synonyms]

VU0080241
1-(2,4-dimethylphenyl)-4-(3-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine
[Molecular Formula]

C19H23N5
[MDL Number]

MFCD03474901
[MOL File]

393845-24-4.mol
[Molecular Weight]

321.42
Chemical PropertiesBack Directory
[Boiling point ]

447.5±45.0 °C(Predicted)
[density ]

1.24±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

4.83±0.30(Predicted)
[color ]

Yellow to orange
Hazard InformationBack Directory
[Description]

VU0080241 is a positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4).
[Uses]

VU0080241 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 4 (mGluR4), with an EC50 of 4.6 μM[1].
[IC 50]

mGlu4: 4.6 μM (EC50)
[References]

[1] Colleen M Niswender, et al. Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4): Part I. Discovery of pyrazolo[3,4-d]pyrimidines as novel mGluR4 positive allosteric modulators. Bioorg Med Chem Lett. 2008 Oct 15; 18(20) DOI:10.1016/j.bmcl.2008.08.087
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