| Identification | Back Directory | [Name]
3,4-DIHYDROXY-5-METHOXYBENZOIC ACID METHYL ESTER | [CAS]
3934-86-9 | [Synonyms]
M3OMG
Bifendate-005
Tryptophan-007
RARECHEM AL BF 0702
METHYL 3,4-DIHYDROXY-5-METHOXYBENZOATE
Methyl 3-methoxy-4,5-dihydroxybenzoate
3,4-DIHYDROXY-5-METHOXYBENZOIC ACID METHYL ESTER
Benzoic acid, 3,4-dihydroxy-5-Methoxy-, Methyl ester | [Molecular Formula]
C9H10O5 | [MDL Number]
MFCD00183269 | [MOL File]
3934-86-9.mol | [Molecular Weight]
198.17 |
| Chemical Properties | Back Directory | [Melting point ]
112-113 °C | [Boiling point ]
391.7±37.0 °C(Predicted) | [density ]
1.337±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Room Temperature | [form ]
Solid | [pka]
8.21±0.23(Predicted) | [color ]
Off-white to yellow |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
1,3-Benzodioxole-5-carboxylic acid, 7-hydroxy-2-oxo--->7-HYDROXY-2,2-DIPHENYL-BENZO[1,3]DIOXOLE-5-CARBOXYLIC ACID METHYL ESTER-->1,3-Benzodioxole-5-carboxylic acid, 2-ethoxy-7-hydroxy-, methyl ester-->METHYL 7-METHOXY-2,2-DIPHENYL-1,3-BENZODIOXOLE-5-CARBOXYLATE-->Gallic acid-->Dimethyl sulfone | [Preparation Products]
1,2-Benzenediol, 3-methoxy-5-(trimethoxymethyl)- |
| Hazard Information | Back Directory | [Uses]
Methyl 3,4-dihydroxy-5-methoxybenzoate is used as intermediates of biphenyl diesters. | [Biological Activity]
Methyl 3,4-dihydroxy-5-methoxybenzoate has antioxidant properties that protect neuronal cells from oxidative damage. | [Synthesis]
Methyl 3,4-dihydroxy-5-methoxybenzoate is synthesizede by esterified with gallic acid and then etherified with dimethyl sulfate. | [in vivo]
Methyl 3-O-methylgallate (M3OMG; 10 and 20 mg/kg, i.p., ) treatment mitigated the NaF-induced oxidative stress through normalization of the level of TBARS, reduced levels of glutathione and by the restoration of the diminished antioxidant enzyme activities[1]. | Animal Model: | Fifty male Wistar rats (8-12 , 7-days old, 200-250 g)[1]. | | Dosage: | 10 and 20 mg/kg. | | Administration: | I.P. for 1 week. | | Result: | Mitigated the NaF-induced oxidative stress through normalization of the level of TBARS, reduced levels of glutathione and by the restoration of the diminished antioxidant enzyme activities. |
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