| Identification | Back Directory | [Name]
Picroside II | [CAS]
39012-20-9 | [Synonyms]
AMPHICOSIDE
PICROSID II
Picroside-2
Picroside a…
Berberine II
PICROSIDE II
PICROSIDE ò
AMPHICOSIDE II
Vanilloyl catalpol
6'-VANILLOYL CATALPOL
Picroside II USP/EP/BP
Picroside II, ≥98% (HPLC)
Picroside II, 98%, from Picrorhiza scrophulariiflora Pennell.
6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl,[1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-
[(1aS)-1a,1bα,2,5aα,6,6aβ-Hexahydro-6α-[(4-hydroxy-3-methoxybenzoyl)oxy]-1aβ-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2α-yl]β-D-glucopyranoside
(1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-β-D-glucopyranoside
β-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl
(1aS-(1aalpha,1bbeta,2beta,5abeta,6beta,6aalpha))-1a,1b,2,5a,6,6a-Hexahydro-6-((4-hydroxy-3-methoxybenzoyl)oxy)-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl-beta-D-glucopyranoside
beta-d-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-[(4-hydroxy-3-methoxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, [1aS-(1aalpha,1bbeta,2beta,5abeta,6beta,6aalpha)]- | [EINECS(EC#)]
254-247-6 | [Molecular Formula]
C23H28O13 | [MDL Number]
MFCD00017402 | [MOL File]
39012-20-9.mol | [Molecular Weight]
512.46 |
| Questions And Answer | Back Directory | [Uses]
Picroside II similar to Picroside I (P437635), acts as an oxygen free radical scavenger and thus promotes anti-inflammatory activity and may be used in the treatment of arthritis or ischemic injury. |
| Chemical Properties | Back Directory | [Melting point ]
145 - 155oC | [Boiling point ]
780.8±60.0 °C(Predicted) | [density ]
1.66±0.1 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
ethanol: soluble1mg/mL, clear, colorless | [form ]
Solid | [pka]
8.07±0.20(Predicted) | [color ]
Pale Yellow | [InChIKey]
AKNILCMFRRDTEY-MRFBWRKESA-N |
| Hazard Information | Back Directory | [Definition]
ChEBI: Picroside ii is a tannin. | [Biological Activity]
Picroside II displaysmany anti-cancer properties such as anti-metastaticanti-angiogenicand anti-apoptotic activities in both in vitro and in vivo studies.It also exerts antioxidantanti-inflammatoryand antidiarrheal effectsagainst acute oxidative injuries such as severe acute pancreatitis-inducedintestinal barrier injury. PII has protective effects onischemia/reperfusion (I/R)-induced injury by interacting with differentmechanisms in various in vitro and in vivo models.''Phytochemical found in Traditional Chinese Medicine herbal preparations. Picroside IIa glucosideis reported to have hepatoprotectivecardioprotectiveand neuroprotective properties. |
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