Identification | Back Directory | [Name]
17-PHENYL TRINOR PROSTAGLANDIN E2 | [CAS]
38315-43-4 | [Synonyms]
CL 116147 17-Phenyl-omega-trinor-PGE2 FOBVMYJQWZOGGJ-XYRJXBATSA-N 17-Phenyl-18,19,20-trinor-PGE2 17-Phenyltrinorprostaglandinee2 17-PHENYL TRINOR PROSTAGLANDIN E2 17-PHENYL-TRINOR-PROSTAGLANDIN E2 98% 17-PHENYL TRINOR PROSTAGLANDIN E2 99+% 17-Phenyl-18,19,20-trinorprostaglandin E2 7-[3-hydroxy-2-(3-hydroxy-5-phenylpent-1-enyl)-5-oxocyclopentyl]hept-5-enoic acid 9-OXO-11ALPHA-15S-DIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROSTA-5Z,13E-DIEN-1-OIC ACID 5-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]-5-oxocyclopentyl]-, (5Z)- | [Molecular Formula]
C23H30O5 | [MDL Number]
MFCD00135219 | [MOL File]
38315-43-4.mol | [Molecular Weight]
386.48 |
Chemical Properties | Back Directory | [Boiling point ]
597.1±50.0 °C(Predicted) | [density ]
1?+-.0.06 g/cm3(Predicted) | [RTECS ]
MJ9681060 | [solubility ]
DMF: >100 mg/ml (from Fluprostenol); DMSO: >100 mg/ml (from Fluprostenol); Ethanol: >100 mg/ml (from Fluprostenol); PBS pH 7.2: >0.8 mg/ml (from 17-phenyl tri | [form ]
Oil | [pka]
4.75±0.10(Predicted) |
Hazard Information | Back Directory | [Uses]
17-Phenyl-trinor-prostaglandin E2 is a synthetic analog of PGE2 and an agonist at the EP1 and EP3 receptor (1). Prostaglandin E2(PGE2) regulates neuroinflammatory responses and is upregulated in brain injury by cyclooxygenase 2 (COX-?2) and membrane-bound PGE synthase. 17-Phenyl-trinor-prostaglandin E2 can be used to investigate inflammatory signaling pathways (2). | [Definition]
ChEBI: 17-phenyl-18,19,20-trinor-prostaglandin E2 is a prostanoid that is 18,19,20-trinor-prostaglandin E2 in which one of the terminal methyl hydrogens has been replaced by a phenyl group. It has a role as a human metabolite and a prostaglandin receptor agonist. It is a prostanoid, an alicyclic ketone, a beta-hydroxy ketone, a secondary alcohol, an oxo monocarboxylic acid, a hydroxy monocarboxylic acid and an olefinic compound. |
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