| Identification | Back Directory | [Name]
15-KETO PROSTAGLANDIN F2ALPHA | [CAS]
35850-13-6 | [Synonyms]
15-ketoprostaglandin F2A
15-keto Prostaglandin F2α
15-Ketoprostaglandinef2alpha
15-oxo-prostaglandin F2alpha
15-KETO PROSTAGLANDIN F2ALPHA
15-keto Prostaglandin F2 MaxSpecStandard
15-keto Prostaglandin F2α MaxSpec? Standard
15-keto Prostaglandin F2α Lipid Maps MS Standard
9ALPHA, 11ALPHA-DIHYDROXY-15-OXO-PROSTA-5Z, 13E-DIEN-1-OIC ACID
9,11-Dihydroxy-15-oxo-[5Z,9α,11α,13E]-prosta-5,13-dien-1-oic acid
Prosta-5,13-dien-1-oic acid, 9,11-dihydroxy-15-oxo-, (5Z,9α,11α,13E)-
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxooct-1-enyl]cyclopentyl]hept-5-enoic acid | [Molecular Formula]
C20H32O5 | [MDL Number]
MFCD00135245 | [MOL File]
35850-13-6.mol | [Molecular Weight]
352.47 |
| Chemical Properties | Back Directory | [Boiling point ]
535.2±50.0 °C(Predicted) | [density ]
1.149±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
100 mg/ml (from PGF2a) in DMF, 100 mg/ml (from PGF2a) in DMSO, 100 mg/ml (from PGF2a) in Ethanol | [form ]
solution | [pka]
4.76±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
15-keto Prostaglandin F2α (15-keto PGF2α) is the first metabolite of PGF2α (Item Nos. 16010 | 10007221). in the 15-hydroxy PGDH pathway. It is one of the critical components in the goldfish and Atlantic salmon postovulatory pheromone.1,2 15-keto PGF2α stimulates the male goldfish and salmon olfactory receptors with detection thresholds of 10-12 and 10-8 M, respectively.1,2 15-keto PGF2α is 10-fold less active than PGF2α in decreasing rabbit intraocular pressure.3
15-keto PGF2α MaxSpec® standard is a quantitative grade standard of 15-keto PGF2α (Item No. 16720) that has been prepared specifically for mass spectrometry or any application where quantitativereproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independentlyprepared calibration standard. This 15-keto PGF2α MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis.Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, itis necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality. | [Uses]
15-keto Prostaglandin F2α (15-keto PGF2α) is the first metabolite of PGF2α. in the 15-hydroxy PGDH pathway. It is one of the critical components in the goldfish and Atlantic salmon postovulatory pheromone. 15-keto PGF2α stimulates the male goldfish and salmon olfactory receptors with detection thresholds of 10-12 and 10-8 M, respectively. 15-keto PGF2α is 10-fold less active than PGF2α in decreasing rabbit intraocular pressure. | [Definition]
ChEBI: A prostaglandin Falpha obtained by formal oxidation of the 15-hydroxy group of prostaglandin F2alpha. | [IC 50]
FP; Human Endogenous Metabolite | [storage]
Store at -20°C |
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