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ChemicalBook--->CAS DataBase List--->346691-38-1

346691-38-1

346691-38-1 Structure

346691-38-1 Structure
IdentificationBack Directory
[Name]

N-(4-butylphenyl)-5-nitrofuran-2-carboxamide
[CAS]

346691-38-1
[Synonyms]

STING-IN-2
STING inhibitor C-170
N-(4-butylphenyl)-5-nitrofuran-2-carboxamide
2-Furancarboxamide, N-(4-butylphenyl)-5-nitro-
Inhibitor,autoinflammatory,STING,ERIS,MPYS,cGAMP,MITA,IFNB1,STING IN 2,Stimulator of Interferon Genes,TMEM173,inhibit,palmitoylation,STINGIN2,p-TBK1,TNF
[Molecular Formula]

C15H16N2O4
[MDL Number]

MFCD00784211
[MOL File]

346691-38-1.mol
[Molecular Weight]

288.3
Chemical PropertiesBack Directory
[Boiling point ]

359.3±37.0 °C(Predicted)
[density ]

1.260±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: Soluble
[form ]

A crystalline solid
[pka]

11.88±0.70(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

STING-IN-2 (C-170) is a potent and covalent STING inhibitor. STING-IN-2 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). STING-IN-2 can be used for autoinflammatory disease research[1].
[storage]

Store at -20°C
[References]

[1] Simone M Haag, et al. Targeting STING with covalent small-molecule inhibitors. Nature. 2018 Jul;559(7713):269-273. DOI:10.1038/s41586-018-0287-8
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