| Identification | Back Directory | [Name]
Trachelogenin | [CAS]
34209-69-3 | [Synonyms]
Trachelogenin
(-)-TRACHELOGENIN
Trachelogenin USP/EP/BP
(3S,4R)-4-(3,4-dimethoxybenzyl)-3-hydroxy-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one
(3S,4S)-4-[(3,4-Dimethoxyphenyl)methyl]dihydro-3-hydroxy-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone | [Molecular Formula]
C21H24O7 | [MDL Number]
MFCD30834715 | [MOL File]
34209-69-3.mol | [Molecular Weight]
388.41 |
| Chemical Properties | Back Directory | [Melting point ]
144 °C | [Boiling point ]
582.7±45.0 °C(Predicted) | [density ]
1.300±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
10.03±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Trachelogenin ((-)-Trachelogenin) is an HCV entry inhibitor without genotype specificity, and with low cytotoxicity. Trachelogenin inhibits HCVcc infection and HCVpp cell entry in a dose-dependent manner with an IC50 of 0.325 and 0.259 μg/mL in HCVcc and HCVpp models, respectively. Trachelogenin exhibits effective antiviral, anti-inflammatory and analgesic effects[1]. | [Definition]
ChEBI: Trachelogenin is a lignan. | [References]
[1] Xi-Jing Qian, et al. Trachelogenin, a novel inhibitor of hepatitis C virus entry through CD81. J Gen Virol. 2016 May;97(5):1134-1144. DOI:10.1099/jgv.0.000432 |
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