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ChemicalBook--->CAS DataBase List--->33889-68-8

33889-68-8

33889-68-8 Structure

33889-68-8 Structure
IdentificationBack Directory
[Name]

Demethyl tetrandrine
[CAS]

33889-68-8
[Synonyms]

Thaligine
Menisidine
Nsc 277171
Thalrugosine
Fangchinoline
Hanfangchin B
(R)-Fangchinoline
d-Isofangchinoline
Demethyl tetrandrine
Berbaman-7-ol, 6,6',12-trimethoxy-2,2'-dimethyl-
16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolin-22-ol, 3,4,4a,5,16a,17,18,19-octahydro-12,21,26-trimethoxy-4,17-dimethyl-, (4aS,16aR)- (9CI)
[Molecular Formula]

C37H40N2O6
[MOL File]

33889-68-8.mol
[Molecular Weight]

608.72
Questions And AnswerBack Directory
[Uses]

Fangchinoline is an isolate from Stephania Tetrandra that shows anti-cancer activity. It inhibits breast adenocarcinoma proliferation through apoptosis induction. In addition, it has been shown to inhibit HIV-Type 1 replication.
Chemical PropertiesBack Directory
[Melting point ]

212-4°C (dec. ).
[Boiling point ]

709.7±60.0 °C(Predicted)
[density ]

1.204±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,2-8°C
[solubility ]

Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly)
[form ]

Solid
[pka]

9.38±0.20(Predicted)
[color ]

Off-White to Pale Beige
Hazard InformationBack Directory
[Description]

Thalictrum rugosum Ait also contains this alkaloid which is dextrorotatory with [o:lbo + 128° (MeOH). The ultraviolet spectrum of this base consists of a single absorption maximum at 283 flI/J..
[target]

DNA/RNA Synthesis
[storage]

4°C, protect from light
[References]

Mitscher et al., Chem. Commun., 589 (1971)
Spectrum DetailBack Directory
[Spectrum Detail]

Demethyl tetrandrine(33889-68-8)1HNMR
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