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ChemicalBook--->CAS DataBase List--->327613-10-5

327613-10-5

327613-10-5 Structure

327613-10-5 Structure
IdentificationBack Directory
[Name]

BIO-7662
[CAS]

327613-10-5
[Synonyms]

BIO-7662
BIO-7662 (BIO 7662
[Molecular Formula]

C38H48N6O8S
[MOL File]

327613-10-5.mol
[Molecular Weight]

748.89
Chemical PropertiesBack Directory
[density ]

1.316±0.06 g/cm3(Predicted)
[pka]

3.52±0.10(Predicted)
Hazard InformationBack Directory
[Description]

BIO-7662 is a potent and highly selective α4β1 integrin antagonist.
[Uses]

BIO7662 is a specific α4β1 antagonist. BIO7662 can be used to study α4β1 integrin-ligand interactions[1][2].
[References]

[1] Egger LA, et al. A small molecule alpha4beta1/alpha4beta7 antagonist differentiates between the low-affinity states of alpha4beta1 and alpha4beta7: characterization of divalent cation dependence. J Pharmacol Exp Ther. 2003 Sep;306(3):903-13. DOI:10.1124/jpet.102.047704
[2] Chen LL,et al. Evidence that ligand and metal ion binding to integrin alpha 4beta 1 are regulated through a coupled equilibrium. J Biol Chem. 2001 Sep 28;276(39):36520-9. DOI:10.1074/jbc.M106216200
327613-10-5 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website: www.targetmol.com/
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
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Website: https://www.targetmol.cn/
Company Name: Nanjing Shizhou Biology Technology Co.,Ltd  
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