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ChemicalBook--->CAS DataBase List--->312-63-0

312-63-0

312-63-0 Structure

312-63-0 Structure
IdentificationBack Directory
[Name]

N-(4-Fluorophenyl)benzenesulfonaMide, 97%
[CAS]

312-63-0
[Synonyms]

ELN484228
NSC 164389
ELN 484228 - NSC 164389
ELN484228, 10 mM in DMSO
4′-Fluorobenzenesulfonanilide
α-Synuclein Blocker, ELN484228
ELN484228;ELN-484228;ELN 484228
N-(p-Fluorophenyl)benzenesulfonamide
Benzenesulfonamide, N-(4-fluorophenyl)-
N-(4-Fluorophenyl)benzenesulfonamide,97%
N-(4-Fluorophenyl)benzenesulfonaMide, 97%
Inhibitor,ELN484228,inhibit,ELN 484228,ELN-484228
α-Synuclein Blocker, ELN484228 - CAS 312-63-0 - Calbiochem
[EINECS(EC#)]

604-604-1
[Molecular Formula]

C12H10FNO2S
[MDL Number]

MFCD00091019
[MOL File]

312-63-0.mol
[Molecular Weight]

251.277
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO: soluble20mg/mL, clear
[form ]

powder
[color ]

white to beige
[Stability:]

Stable under recommended storage conditions., Stable Under Recommended Storage C
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H319
[Precautionary statements ]

P264-P270-P280-P301+P312-P305+P351+P338-P337+P313
[Hazard Codes ]

Xn
[Risk Statements ]

22-36
[Safety Statements ]

26
Hazard InformationBack Directory
[Uses]

ELN484228, is α-synuclein blocker. α-Synucleinis a key protein in Parkinson’s disease.
[Biological Activity]

ELN484228 is a cell penetrant α-synuclein ligand th at rescues of α-synuclein induced disruption of vesicle trafficking and dopaminergic neuronal loss and neurite retraction. ELN484228 reverses a-synuclein induced impairment of phagocytosis and protects dopaminergic neurons against the toxic effects of α-synuclein A53T over-expression.
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