| Identification | Back Directory | [Name]
3,4-dimethoxy-N-(5-methyl-1,2-oxazol-3-yl)benzamide | [CAS]
309951-18-6 | [Synonyms]
WAY-309060
WAY-309060（BRD4 Inhibitor-24）
3,4-Dimethoxy-N-(5-methylisoxazol-3-yl)benzamide
3,4-dimethoxy-N-(5-methyl-1,2-oxazol-3-yl)benzamide
Benzamide, 3,4-dimethoxy-N-(5-methyl-3-isoxazolyl)-
Inhibitor,WAY309060,MCF7,BRD4 Inhibitor-24,antitumor,Epigenetic Reader Domain,inhibit,breast cancer,K652,WAY 309060,leukemia | [Molecular Formula]
C13H14N2O4 | [MDL Number]
MFCD01355072 | [MOL File]
309951-18-6.mol | [Molecular Weight]
262.26 |
| Chemical Properties | Back Directory | [Boiling point ]
360.1±42.0 °C(Predicted) | [density ]
1.257±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [form ]
Solid | [pka]
11.54±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
BRD4 Inhibitor-24 (compound 3U) is a potent BRD4 inhibitor, BRD4 Inhibitor-24 shows antitumor activity against MCF7 and K652 cells, with IC50 values of 33.7 and 45.9 μM, respectively (extracted from patent CN107721975A)[1]. | [IC 50]
BRD4 | [storage]
4°C, protect from light | [References]
[1] Yao Zhiyi, et al. BRD4 micromolecular inhibitors, synthetic method and its application with antitumor activity. CN107721975A |
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