| Identification | Back Directory | [Name]
2'-F-N2-ibu-2'-ara-dG | [CAS]
308356-20-9 | [Synonyms]
2'-F-N2-ibu-2'-ara-dG
N2-iso-Butyroyl-2'-fluoro-2'-deoxyarabinoguanosine
Propanamide, N-[9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methyl- | [Molecular Formula]
C14H18FN5O5 | [MOL File]
308356-20-9.mol | [Molecular Weight]
355.33 |
| Hazard Information | Back Directory | [Uses]
N2-iso-Butyroyl-2’-fluoro-2’-deoxyarabinoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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