| Identification | Back Directory | [Name]
Arg-AMS | [CAS]
301351-95-1 | [Synonyms]
Arg-AMS
Adenosine, 5'-[[(2S)-2-amino-5-[(aminoiminomethyl)amino]-1-oxopentyl]sulfamate] (9CI) | [Molecular Formula]
C16H26N10O7S | [MDL Number]
MFCD31746901 | [MOL File]
301351-95-1.mol | [Molecular Weight]
502.51 |
| Chemical Properties | Back Directory | [density ]
2.00±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : ≥ 100 mg/mL (199.00 mM) | [form ]
Solid | [pka]
1.24±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Arg-AMS (compound 24) is a potent nanomolar inhibitor of arginyl tRNA synthetase, which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes[1]. | [References]
[1] Kasai S, et al. Functional profiling of adenylation domains in nonribosomal peptide synthetases by competitive activity-based protein profiling. Chem Commun (Camb). 2015 Nov 11;51(87):15764-7. DOI:10.1039/c5cc04953a |
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