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ChemicalBook--->CAS DataBase List--->29705-92-8

29705-92-8

29705-92-8 Structure

29705-92-8 Structure
IdentificationBack Directory
[Name]

EXPERIMENTAL ALLERGIC ENCEPHALITOGENIC PEPTIDE (HUMAN)
[CAS]

29705-92-8
[Synonyms]

EAE
allergic peptide
H2N-FSWGAEGQR-OH
EAE-PEPTIDE (HUMAN)
FRAG 114-122 HUMAN MYELIN PROTEIN
PHE-SER-TRP-GLY-ALA-GLU-GLY-GLN-ARG
H-PHE-SER-TRP-GLY-ALA-GLU-GLY-GLN-ARG-OH
H2N-PHE-SER-TRP-GLY-ALA-GLU-GLY-GLN-ARG COOH
MYELIN BASIC PROTEIN (115-123) [HOMO SAPIENS]
EXPERIMENTAL ALLERGIC ENCEPHALITOGENIC PEPTIDE
EXPERIMENTAL ALLERGIC ENCEPHALITOGENIC PEPTIDE (HUMAN)
ExperiMental Allergic Encephalitogenic Peptide (huMan) EAE-Peptide (huMan)
L-Arginine, L-phenylalanyl-L-seryl-L-tryptophylglycyl-L-alanyl-L-α-glutamylglycyl-L-glutaminyl-
(4S)-5-[[2-[[(2S)-5-amino-1-[[(1S)-1-carboxy-4-(diaminomethylideneamino)butyl]amino]-1,5-dioxopentan-2-yl]amino]-2-oxoethyl]amino]-4-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1~{H}-indol-3-yl)propanoyl]amino]acetyl]amino]propanoyl]amino]-5-oxopentanoic acid
[Molecular Formula]

C46H64N14O14
[MDL Number]

MFCD00076852
[MOL File]

29705-92-8.mol
[Molecular Weight]

1037.09
Chemical PropertiesBack Directory
[density ]

1.52±0.1 g/cm3(Predicted)
[storage temp. ]

-15°C
[pka]

3.30±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Experimental allergic encephalitogenic peptide (human) is a EAE peptide. Experimental allergic encephalitogenic peptide (human) induces encephalomyelitis in guinea pigs[1].
[in vivo]

Experimental allergic encephalitogenic peptide (human) (30 μg; intracutaneous injection; once) with Freund adjuvant induces the onset of encephalomyelitis on day 9-19 after the injection in guinea pigs, the lethality is 33%[1].

[References]

[1] encephalitogenic determinant. Cell Immunol. 1975 Jan;15(1):143-51. DOI:10.1016/0008-8749(75)90171-9
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