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ChemicalBook--->CAS DataBase List--->2754265-76-2

2754265-76-2

2754265-76-2 Structure

2754265-76-2 Structure
IdentificationBack Directory
[Name]

Benzamide, 2-methoxy-N-(3-methoxyphenyl)-4-(1H-pyrrolo[2,3-b]pyridin-5-yl)-
[CAS]

2754265-76-2
[Synonyms]

TNIK-IN-2
inhibit,Inhibitor,TNIKIN2,TNIK IN 2,TNIK
Benzamide, 2-methoxy-N-(3-methoxyphenyl)-4-(1H-pyrrolo[2,3-b]pyridin-5-yl)-
[Molecular Formula]

C22H19N3O3
[MOL File]

2754265-76-2.mol
[Molecular Weight]

373.4
Chemical PropertiesBack Directory
[density ]

1.299±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

12.88±0.70(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

TNIK-IN-2 is a Traf2- and Nck-interacting protein kinase (TNIK) inhibitor, with an IC50 of 1.3337 μM[1].
[References]

[1] Li Y, et, al. Discovery of 3,4-Dihydrobenzo[ f][1,4]oxazepin-5(2 H)-one Derivatives as a New Class of Selective TNIK Inhibitors and Evaluation of Their Anti-Colorectal Cancer Effects. J Med Chem. 2022 Jan 5. DOI:10.1021/acs.jmedchem.1c00672
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