| Identification | Back Directory | [Name]
thonningianin B | [CAS]
271579-12-5 | [Synonyms]
thonningianin B
1-Propanone, 1-[4-[[4,6-O-[[(1S)-4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-diyl]dicarbonyl]-β-D-glucopyranosyl]oxy]-2,6-dihydroxyphenyl]-3-phenyl- | [Molecular Formula]
C35H30O17 | [MOL File]
271579-12-5.mol | [Molecular Weight]
722.61 |
| Chemical Properties | Back Directory | [Boiling point ]
1239.4±65.0 °C(Predicted) | [density ]
1.670±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
6.80±0.40(Predicted) | [color ]
Light yellow to light brown |
| Hazard Information | Back Directory | [Uses]
Thonningianin B is an antioxidant and an autophagy enhancer[1][2]. | [References]
[1] Ohtani II, et al. Thonningianins A and B, new antioxidants from the African medicinal herb Thonningia sanguinea. J Nat Prod. 2000 May;63(5):676-9. DOI:10.1021/np990396w
[2] Zhou XG, et al. Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer's disease. Inflamm Regen. 2022 Aug 3;42(1):25. DOI:10.1186/s41232-022-00209-7 |
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