Identification | Back Directory | [Name]
Pyrido[2,3-d]pyrimidin-2(1H)-one, 4-[(2R,6R)-4-[(2S)-2-aziridinylcarbonyl]-2,6-dimethyl-1-piperazinyl]-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]- | [CAS]
2648552-62-7 | [Synonyms]
KRAS G12D inhibitor 13 Pyrido[2,3-d]pyrimidin-2(1H)-one, 4-[(2R,6R)-4-[(2S)-2-aziridinylcarbonyl]-2,6-dimethyl-1-piperazinyl]-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]- | [Molecular Formula]
C31H33F2N7O3 | [MOL File]
2648552-62-7.mol | [Molecular Weight]
589.64 |
Hazard Information | Back Directory | [Uses]
KRAS G12D inhibitor 13 is a potent inhibitor of KRAS G12D. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12D inhibitor 13 has the potential for the research of KRAS G12D-mediated cancer (extracted from patent WO2021108683A1, compound 142)[1]. | [References]
[1] Jennifer PITZEN, et al. Covalent ras inhibitors and uses thereof. Patent WO2021108683A1. |
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