| Identification | Back Directory | [Name]
NSC-703786 | [CAS]
260443-89-8 | [Synonyms]
5F203
5F-203
NSC-703786
5-fluoro 203
5F 203
(5F-203
4-(5-Fluorobenzothiazol-2-yl)-2-methylphenylamine
4-(5-Fluoro-2-benzothiazolyl)-2-methyl-benzenamine
4-(5-fluoro-1,3-benzothiazol-2-yl)-2-methylaniline
Benzenamine, 4-(5-fluoro-2-benzothiazolyl)-2-methyl- | [Molecular Formula]
C14H11FN2S | [MDL Number]
MFCD06407710 | [MOL File]
260443-89-8.mol | [Molecular Weight]
258.31 |
| Hazard Information | Back Directory | [Uses]
5-Fluoro 203 is a cytotoxic agent which actiates AhR signaling, inducing transcription of CYP1A1 which leads to the formation of DNA adducts and cell cycle arrest. | [Biological Activity]
5F-203 is a cytotoxic molecule th at forms DNA adducts th at lead to cell death. 5F-203 induces aryl hydrocarbon receptor signalingand elevates expression of CYP1A1. Treatment of cells with 5F-203 also leads to elevation of reactive oxygen species and activation of p38JNK and ERK. |
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| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Lynnchem
|
| Tel: |
86-(0)29-85992781 17792393971 |
| Website: |
http://www.lynnchem.com/ |
|