| Identification | Back Directory | [Name]
(3R)-3-(2-methylpropanoyloxy)-4-trimethylazaniumylbutanoate | [CAS]
25518-49-4 | [Synonyms]
Isobutyryl-L-carnitine
isobutyryl-1-carnitine
O-isobutyryl-L-carnitine
Isobutyryl-L-carnitine >=97.0% (TLC)
(3R)-3-(2-methylpropanoyloxy)-4-trimethylazaniumylbutanoate | [Molecular Formula]
C11H21NO4 | [MDL Number]
MFCD01674829 | [MOL File]
25518-49-4.mol | [Molecular Weight]
231.289 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [solubility ]
DMSO: 250 mg/mL (1080.89 mM); Water: 125 mg/mL (540.45 mM) | [form ]
powder | [color ]
white | [optical activity]
[α]/D -22±2°, c = 1 in H2O | [BRN ]
4138517 |
| Safety Data | Back Directory | [RTECS ]
BP2993000 | [Toxicity]
mouse,LD50,subcutaneous,9600mg/kg (9600mg/kg),Acta Biologica et Medica Germanica. Vol. 26, Pg. 1237, 1971. |
| Hazard Information | Back Directory | [Uses]
Isobutyryl-L-carnitine may be used as an analytical reference standard for the separation and identification of underivatized isobutyryl-L-carnitine in human plasma samples using high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC-MS/MS). It may also be used as an analytical reference standard for the quantification of the analyte in human urine samples using liquid chromatography/electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS). | [Definition]
ChEBI: An optically active form of O-isobutyrylcarnitine having (R)-configuration. | [General Description]
Isobutyryl-L-carnitine belongs to the acylcarnitines class of compounds. These compounds are produced from L-carnitine, which plays an important role in fatty acid metabolic pathways. The functions and roles of acyl-L-carnitines in various tissues like brain, heart, and muscle continue to attract much interest. | [Biochem/physiol Actions]
Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases (ACADs), which are a group of mitochondrial enzymes involved in the metabolism of fatty acids or branched-chain amino acids. | [IC 50]
Human Endogenous Metabolite | [storage]
Store at -20°C |
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