| Identification | Back Directory | [Name]
FIBRINOPEPTIDE A, HUMAN | [CAS]
25422-31-5 | [Synonyms]
FPA, HUMAN
FIBRINOPEPTIDE A
ADSGEGDFLAEGGGVR
Human fibrinopeptide A
fibrinogen alphaA(1-16)
ADSGEGDFLAEGGGVR, HUMAN
FIBRINOPEPTIDE A, HUMAN
FIBRINOPEPTIDE A, HUMAN USP/EP/BP
ALA-ASP-SER-GLY-GLU-GLY-ASP-PHE-LEU-ALA-GLU-GLY-GLY-VAL-ARG
ALA-ASP-SER-GLY-GLU-GLY-ASP-PHE-LEU-ALA-GLU-GLY-GLY-GLY-VAL-ARG
Ala-Asp-Ser-Gly-Glu-Gly-Asp-Phe-Leu-Ala-Glu-Gly-Gly-Gly-Val-Arg-OH
H-ALA-ASP-SER-GLY-GLU-GLY-ASP-PHE-LEU-ALA-GLU-GLY-GLY-GLY-VAL-ARG-OH
ALA-ASP-SER-GLY-GLU-GLY-ASP-PHE-LEU-ALA-GLU-GLY-GLY-GLY-VAL-ARG HUMAN
L-Ala-L-Asp-L-Ser-Gly-L-Glu-Gly-L-Asp-L-Phe-L-Leu-L-Ala-L-Glu-Gly-Gly-Gly-L-Val-L-Arg-OH | [Molecular Formula]
C63H97N19O26 | [MDL Number]
MFCD00076437 | [MOL File]
25422-31-5.mol | [Molecular Weight]
1536.56 |
| Hazard Information | Back Directory | [Uses]
Fibrinopeptide A human has been used for protein control experiments performed during sandwich ELISA microarray assay to distinguish between plasma and serum fibrinogen samples. It has also been used in a peptide mixture along with BSA (bovine serum albumin) to ascertain the relation between fragmentation voltage and peptide ion drift time for IMS-MS (ion mobility spectrometry coupled with mass spectrometry). | [General Description]
Fibrinopeptide A (FPA) is produced from the N-terminal Aα region of fibrinogen protein, on cleavage by thrombin. It is composed of 16 amino acids. | [Biochem/physiol Actions]
Fibrinogen plays essential roles in coagulation of blood, wound healing, platelet aggregation and has roles in various other physiological processes. Increase in the levels of fibrinopeptide A (FPA) is found in multiple disorders such as coronary artery disease, disseminated intravascular coagulation, arterial thrombosis, deep venous thrombosis and cancers. | [in vivo]
Fibrinopeptide A (FPA) is a small polypeptide cleaved from fibrinogen by thrombin, has a short half-life, and is considered a sensitive biochemical marker of thrombin activity, fibrin generation, and ongoing thrombosis[2]. |
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