| Identification | Back Directory | [Name]
ATPO | [CAS]
252930-37-3 | [Synonyms]
(S)-ATPO
ATPO solid
3-[5-tert-butyl-3-(phosphonoMethoxy)-4-isoxazolyl]alanine
2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-1,2-oxazol-4-yl]propanoic acid
4-Isoxazolepropanoic acid, α-amino-5-(1,1-dimethylethyl)-3-(phosphonomethoxy)-, (αS)-
(alphaS)-alpha-Amino-5-(1,1-dimethylethyl)-3-(phosphonomethoxy)-4-isoxazolepropanoic acid | [EINECS(EC#)]
604-604-1 | [Molecular Formula]
C11H19N2O7P | [MDL Number]
MFCD03452828 | [MOL File]
252930-37-3.mol | [Molecular Weight]
322.25 |
| Chemical Properties | Back Directory | [Boiling point ]
569.2±60.0 °C(Predicted) | [density ]
1.443±0.06 g/cm3(Predicted) | [solubility ]
1 M NaOH: 7 mg/mL, soluble | [form ]
solid | [pka]
1.92±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
(S)-ATPO is the (S)-enantiomer of ATPO, which is a competitive antagonist at GluR1-4 (AMPA-preferring) receptors[1]. | [References]
[1] Hogner A, et al. Competitive antagonism of AMPA receptors by ligands of different classes: crystal structure of ATPO bound to the GluR2 ligand-binding core, in comparison with DNQX. J Med Chem. 2003;46(2):214-221. DOI:10.1021/jm020989v |
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