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ChemicalBook--->CAS DataBase List--->2513289-74-0

2513289-74-0

2513289-74-0 Structure

2513289-74-0 Structure
IdentificationBack Directory
[Name]

BSJ-04-122
[CAS]

2513289-74-0
[Synonyms]

BSJ-04-122
2-Propenamide, N-[2-[(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]phenyl]-
[Molecular Formula]

C15H12ClN5O
[MOL File]

2513289-74-0.mol
[Molecular Weight]

313.75
Chemical PropertiesBack Directory
[density ]

1.486±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

11.11±0.50(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

BSJ-04-122 is a covalent MKK4/7 dual inhibitor. BSJ-04-122 inhibits MKK4 and MKK7 with IC50 values of 4 nM and 181 nM, respectively. BSJ-04-122 can be used for the research of cancer[1].
[References]

[1] Jie Jiang, et al. Discovery of Covalent MKK4/7 Dual Inhibitor. Cell Chem Biol DOI:10.1016/j.chembiol.2020.08.014
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