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LC 2 Epimer is a negative control for LC 2. | [Uses]
LC-2 epimer is a differential isomer of LC-2. LC-2 is a mutation-selective PROTAC depressant for KRAS and contains a ligand for the von Hippel Lindau E3 ligase linked to the KRAS inhibitor MRTX849[1]. | [storage]
Store at -20°C | [References]
[1] Bond MJ, et al. Targeted Degradation of Oncogenic KRASG12C by VHL-Recruiting PROTACs. ACS Cent Sci. 2020 Aug 26;6(8):1367-1375. DOI:10.1021/acscentsci.0c00411 |
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Company Name: |
R&D Systems, Inc
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18003437475 18003437475 |
Website: |
www.rndsystems.com |
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