| Identification | Back Directory | [Name]
4'-thioadenosine | [CAS]
2500-80-3 | [Synonyms]
Nsc 82219
4'-thioadenosine
Adenosine, 4'-thio-
(2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrothiophene-3,4-diol | [Molecular Formula]
C10H13N5O3S | [MDL Number]
MFCD28342914 | [MOL File]
2500-80-3.mol | [Molecular Weight]
283.31 |
| Hazard Information | Back Directory | [Uses]
4’-Thioadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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