| Identification | Back Directory | [Name]
(S)-METHYL-2-NAPHTHOYLAMINO-3-(4-NITROPHENYL)PROPIONATE | [CAS]
247580-43-4 | [Synonyms]
SB 328437
SB 328437 >=98% (HPLC)
SB 328437 - CAS 247580-43-4 - Calbiochem
(S)-METHYL-2-NAPHTHOYLAMINO-3-(4-NITROPHENYL)PROPIONATE
Methyl (2S)-2-(1-naphthoylaMino)-3-(4-nitrophenyl)propanoate
N-(1-Naphthalenylcarbonyl)-4-nitro-L-phenylalaninemethylester
L-Phenylalanine, N-(1-naphthalenylcarbonyl)-4-nitro-, methyl ester | [Molecular Formula]
C21H18N2O5 | [MDL Number]
MFCD03453566 | [MOL File]
247580-43-4.mol | [Molecular Weight]
378.38 |
| Chemical Properties | Back Directory | [Boiling point ]
642.9±50.0 °C(Predicted) | [density ]
1.305±0.06 g/cm3(Predicted) | [storage temp. ]
Store at +4°C | [solubility ]
DMSO: ≥10mg/mL | [form ]
White solid | [pka]
12.51±0.46(Predicted) | [color ]
white to tan |
| Hazard Information | Back Directory | [Uses]
SB 328437 is a potent and selective CCR3 receptor antagonist. | [Biological Activity]
SB 328437 inhibits the recruitment and migration of eosinophils in allergen models of models. It suppresses the Th2-mediated eosinophil infiltration in the airways.''SB-328437 is a potentselective CCR-3 antagonist (IC50 = 1.6 nM). The compound blockes CCR3 agonist-induced calcium mobilization in CCR3 expressing cells with the following IC50 values: eotaxin38 nM; eotaxin-235 nM and MCP420 nM. | [storage]
Store at +4°C |
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| Company Name: |
DC Chemicals
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| Tel: |
021-58447131 13564518121 |
| Website: |
http://m.approvedhomemanagement.com/ShowSupplierProductsList927327/0.htm |
| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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