| Identification | Back Directory | [Name]
(BETA,BETA-DIMETHYLACRYL)SHIKONIN | [CAS]
24502-79-2 | [Synonyms]
BATA
dmask
Isoarnebin I
Senecioylshikonin
Dimethylacrylshikonin
b,b-DiMethylacrylshikonin
(β,β-Dimethylacry)shikonin
(+)-yl)-4-methyl-3-pentenyleste
(BETA,BETA-DIMETHYLACRYL)SHIKONIN
(beta,beta-Dimethylacryl)shikonine
SHIKONIN-BETA,BETA-DIMETHYLACRYLATE
2-butenoicacid,3-methyl-,1-(1,4-dihydro-5,8-dihydroxy-1,4-dioxo-2-naphthalen
(β,β-Dimethylacryl)shikonin, 98%, from Lithospermum erythrorhizon Sieb. & Zucc.
5,8-DIHYDROXY-2-[1-(BETA,BETA-DIMETHYLACRYLOYLOXY)-4-METHYL-3-PENTENYL]-1,4-NAPHTHALENEDIONE
(R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methylpent-3-en-1-yl 3-methylbut-2-enoate
(+)-3-Methyl-2-butenoic acid 1-(1,4-dihydro-5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methyl-3-pentenyl ester
3-Methyl-2-butenoic acid (R)-1-(1,4-dihydro-5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methyl-3-pentenyl ester
3-Methyl-2-butenoic acid (1R)-1-(1,4-dihydro-5,8-dihydroxy-1,4-dioxo-2-naphthalenyl)-4-methyl-3-penten-1-yl ester | [Molecular Formula]
C21H22O6 | [MDL Number]
MFCD00143687 | [MOL File]
24502-79-2.mol | [Molecular Weight]
370.4 |
| Chemical Properties | Back Directory | [Melting point ]
103°C | [Boiling point ]
587.3±50.0 °C(Predicted) | [density ]
1.269 | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMSO (Slightly, Sonicated), Chloroform (Slightly), Methanol (Slightly, Sonicated | [form ]
Solid | [pka]
7.07±0.20(Predicted) | [color ]
Very Dark Red to Very Dark Brown | [Stability:]
Air Sensitive, Light Sensitive | [InChIKey]
BATBOVZTQBLKIL-QGZVFWFLSA-N | [LogP]
3.130 (est) | [CAS DataBase Reference]
24502-79-2 |
| Hazard Information | Back Directory | [Uses]
(β, β-Dimethylacryl)shikonin is a useful compound in the discovery and study of FFA4 agonists from Arnebia euchroma. | [Definition]
ChEBI: Beta,beta-Dimethylacrylshikonin is a hydroxy-1,4-naphthoquinone. | [Biological Activity]
β,β-Dimethylacrylshikonin (Arnebin-1) is a main active naphthoquinone from herbal plants Lithospermum erythrorhizon (Zicao) and Arnebia euchroma th at exhibits anti-neoplasm and antihyperglycemic activities. It stimulates autophagy in lung adenocarcinoma cells through activation of CaMKKβ-AMPK-mTOR pathway. β,β-Dimethylacrylshikonin facilitates wound healing through PI3K pathway. β,β-Dimethylacrylshikonin improves nonalcoholic fatty liver disease induced by a high-f at diet in rats. |
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