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ChemicalBook--->CAS DataBase List--->2438637-61-5

2438637-61-5

2438637-61-5 Structure

2438637-61-5 Structure
IdentificationBack Directory
[Name]

2(1H)-Pyridinone, 4-[(2,6-dichlorophenyl)thio]-3-[(1,3-dihydro-5,6-dimethoxy-2H-isoindol-2-yl)carbonyl]-6-(trifluoromethyl)-
[CAS]

2438637-61-5
[Synonyms]

2(1H)-Pyridinone, 4-[(2,6-dichlorophenyl)thio]-3-[(1,3-dihydro-5,6-dimethoxy-2H-isoindol-2-yl)carbonyl]-6-(trifluoromethyl)-
[Molecular Formula]

C23H17Cl2F3N2O4S
[MDL Number]

MFCD32062681
[MOL File]

2438637-61-5.mol
[Molecular Weight]

545.36
Chemical PropertiesBack Directory
[Boiling point ]

628.7±55.0 °C(Predicted)
[density ]

1.57±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 8.33 mg/mL (15.27 mM; Need ultrasonic)
[form ]

Solid
[pka]

5.43±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation, with an EC50 of 3.8 nM[1].
[References]

[1] Kyle R. Simonetta, et al. Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nature Communications. 2019 March.
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