| Identification | Back Directory | [Name]
Thalidomide-O-PEG4-NHS ester | [CAS]
2411681-88-2 | [Synonyms]
Thalidomide-O-PEG4-NHS ester | [Molecular Formula]
C28H33N3O13 | [MDL Number]
MFCD32670310 | [MOL File]
2411681-88-2.mol | [Molecular Weight]
619.57 |
| Hazard Information | Back Directory | [Description]
Thalidomide-O-PEG4-NHS ester is a synthesized compound that incorporates the Thalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology it is reactive with amine moiety. | [Uses]
Thalidomide-O-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
Cereblon | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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