| Identification | Back Directory | [Name]
N6-(3-Trifluoromethylbenzyl)adenosine | [CAS]
23661-03-2 | [Synonyms]
Antiviral agent 24
N-(3-trifluoromethylbenzyl)adenosine
N6-(3-Trifluoromethylbenzyl)adenosine
Adenosine, N-?[[3-?(trifluoromethyl)?phenyl]?methyl]?- | [Molecular Formula]
C18H18F3N5O4 | [MOL File]
23661-03-2.mol | [Molecular Weight]
425.36 |
| Hazard Information | Back Directory | [Uses]
Antiviral agent 24 is a potent antiviral agent with EC50 values of 0.101, 19.9, 91.2 μM for EV71, CVA21, EV68, respectively. Antiviral agent 24 inhibits METTL3/METTL14 activity in a dose-dependent manner[1]. | [References]
[1] Salerno M, et al. Rational design of novel nucleoside analogues reveals potent antiviral agents for EV71. Eur J Med Chem. 2022 Nov 24;246:114942. DOI:10.1016/j.ejmech.2022.114942 |
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