| Identification | Back Directory | [Name]
2-amino-3-(4-chlorophenyl)propionic acid hydrochloride | [CAS]
23633-07-0 | [Synonyms]
DL-4-CHLOROPHENYLALANINE HCL
DL-p-Chlorophenylalanine-hydrochloride
2-Amino-3-(4-Chlorophenyl)propionic acid HCl
Dl-4-Chlorophenylalanine Hydrochloric Acid Salt
2-amino-3-(4-chlorophenyl)propanoic acid hydrochloride
2-amino-3-(4-chlorophenyl)propionic acid hydrochloride | [Molecular Formula]
C9H11Cl2NO2 | [MDL Number]
MFCD01674282 | [MOL File]
23633-07-0.mol | [Molecular Weight]
236.095 |
| Hazard Information | Back Directory | [Uses]
Fenclonine hydrochloride is a selective and irreversible tryptophan hydroxylase inhibitor, which is a rate-limiting enzyme in the biosynthesis of serotonin. Fenclonine hydrochloride can be used in carcinoid syndrome research[1][2][3]. | [References]
[1] M Jouvet. Sleep and serotonin: an unfinished story. Neuropsychopharmacology. 1999 Aug;21(2 Suppl):24S-27S. DOI:10.1016/S0893-133X(99)00009-3
[2] A K Sanyal, et al. Prostaglandins: antinociceptive effect of prostaglandin E1 in the rat. Clin Exp Pharmacol Physiol. 1977 May-Jun;4(3):247-55. DOI:10.1111/j.1440-1681.1977.tb02621.x
[3] Shyamshree S S Manna, et al. Paracetamol potentiates the antidepressant-like and anticompulsive-like effects of fluoxetine. Behav Pharmacol. 2015 Apr;26(3):268-81. DOI:10.1097/FBP.0000000000000104
[4] Zheng Y, et al. In silico Analysis and Experimental Validation of Lignan Extracts from Kadsura longipedunculata for Potential 5-HT1AR Agonists. PLoS One. 2015 Jun 15;10(6):e0130055. DOI:10.1371/journal.pone.0130055 |
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