| Identification | Back Directory | [Name]
INDEX NAME NOT YET ASSIGNED | [CAS]
2357108-05-3 | [Synonyms]
XUN-08053
4-((3-azidopropyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione | [Molecular Formula]
C16H16N6O4 | [MOL File]
2357108-05-3.mol | [Molecular Weight]
356.34 |
| Hazard Information | Back Directory | [Description]
XUN-08053 is a functionalized cereblon ligand for PROTAC? research and development. It incorporates an E3 ligase ligand plus an alkylC3 linker with terminal azide ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has no formal name. | [Uses]
Pomalidomide 4'-alkylC3-azide (compound 2a) is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide 4'-alkylC3-azide can be used in the synthesis of PROTAC[1]. | [storage]
Store at -20°C | [References]
[1] Liu H, et al. Construction of an IMiD-based azide library as a kit for PROTAC research. Org Biomol Chem. 2021 Jan 6;19(1):166-170. DOI:10.1039/d0ob02120b |
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| Company Name: |
R&D Systems, Inc
|
| Tel: |
18003437475 18003437475 |
| Website: |
www.rndsystems.com |
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