| Chemical Properties | Back Directory | [Boiling point ]
763.8±60.0 °C(Predicted) | [density ]
1.114±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
4.28±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
m-PEG17-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [Biological Activity]
m-PEG17-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | [IC 50]
PEGs | [References]
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
|
| Company Name: |
Henan Alpha Chemical Co., Ltd.
|
| Tel: |
0371-55055611 18137792234 |
| Website: |
http://m.approvedhomemanagement.com/ShowSupplierProductsList31206/0.htm |
|