| Identification | Back Directory | [Name]
11-DEOXOJERVINEBETA-D-GLUCOSIDE | [CAS]
23185-94-6 | [Synonyms]
(23R)-17,23-epoxy-veratra-5,12-dien-3β-yl β-D-glucopyranoside
β-D-Glucopyranoside, (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3',6',10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-3-yl | [Molecular Formula]
C33H51NO7 | [MDL Number]
MFCD30834740 | [MOL File]
23185-94-6.mol | [Molecular Weight]
573.76 |
| Hazard Information | Back Directory | [Uses]
Cycloposine is a steroidal alkaloid that can be found in the roots and rhizomes of Veratrum californicum. Cycloposine is also a teratogenic compound that may induce cyclopia in pregnant Mianyang embryos[1]. | [References]
[1] Chandler CM, et, al. Improved extraction and complete mass spectral characterization of steroidal alkaloids from Veratrum californicum. Nat Prod Commun. 2013 Aug;8(8):1059-64. PMID:24079166
[2] Keeler RF. Teratogenic compounds of Veratrum californicum (Durand). VII. The structure of the glycosidic alkaloid cycloposine. Steroids. 1969 May;13(5):579-88. DOI:10.1016/s0039-128x(69)80012-7
[3] Heretsch P, et al. Cyclopamine and hedgehog signaling: chemistry, biology, medical perspectives. Angew Chem Int Ed Engl. 2010 May 3;49(20):3418-27. DOI:10.1002/anie.200906967 |
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