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ChemicalBook--->CAS DataBase List--->2309762-40-9

2309762-40-9

2309762-40-9 Structure

2309762-40-9 Structure
IdentificationBack Directory
[Name]

AZ7550 hydrochloride
[CAS]

2309762-40-9
[Synonyms]

AZ7550 hydrochloride
[Molecular Formula]

C??H??ClN?O?
[MDL Number]

MFCD32693953
[MOL File]

2309762-40-9.mol
[Molecular Weight]

522.05
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 1.88 mg/mL (3.60 mM)
[form ]

Solid
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

AZ7550 hydrochloride is an active metabolite of AZD9291 and inhibits the activity of IGF1R with an IC50 of 1.6 μM.
[storage]

Store at -20°C
[References]

[1] Finlay MR, et al. Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor. J Med Chem. 2014 Oct 23;57(20):8249-67. DOI:10.1021/jm500973a
Spectrum DetailBack Directory
[Spectrum Detail]

AZ7550 hydrochloride(2309762-40-9)1HNMR
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