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ChemicalBook--->CAS DataBase List--->2270866-73-2

2270866-73-2

2270866-73-2 Structure

2270866-73-2 Structure
IdentificationBack Directory
[Name]

Cyanine7.5 maleimide
[CAS]

2270866-73-2
[Synonyms]

Cy7.5 mal
Cyanine7.5 mal
Cyanine7.5 maleimide
[Molecular Formula]

C51H55ClN4O3
[MOL File]

2270866-73-2.mol
[Molecular Weight]

807.48
Chemical PropertiesBack Directory
[solubility ]

可溶于氯仿,甲醇,乙腈,DMF等有機(jī)溶劑,難溶于水
[form ]

Solid
[color ]

Green to dark green
[Appearance]

Green solid
[ex/em]

788/808 nm (PBS buffer)
[ε(extinction coefficient)]

223000 L?mol?1?cm?1
[Φ(quantum yield)]

0.10
Hazard InformationBack Directory
[Uses]

Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis[1]. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance[2].
[References]

[1] Yongzhi Men, et al. Biodegradable Zwitterionic Nanogels with Long Circulation for Antitumor Drug Delivery. ACS Appl Mater Interfaces. 2018 Jul 18;10(28):23509-23521. DOI:10.1021/acsami.8b03943
[2] Ptaszek M. Rational design of fluorophores for in vivo applications. Prog Mol Biol Transl Sci. 2013;113:59-108. DOI:10.1016/B978-0-12-386932-6.00003-X
[3] Shindy, H. A. (2017). Fundamentals in the chemistry of cyanine dyes: A review. Dyes and Pigments, 145, 505–513. doi:10.1016/j.dyepig.2017.06.029
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