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ChemicalBook--->CAS DataBase List--->2260791-14-6

2260791-14-6

2260791-14-6 Structure

2260791-14-6 Structure
IdentificationBack Directory
[Name]

OSMI-4
[CAS]

2260791-14-6
[Synonyms]

OSMI-4
[Molecular Formula]

C27H26ClN3O7S2
[MDL Number]

MFCD31813742
[MOL File]

2260791-14-6.mol
[Molecular Weight]

604.09
Chemical PropertiesBack Directory
[density ]

1.414±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 125 mg/mL (206.92 mM)
[form ]

Solid
[pka]

8.27±0.20(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

OSMI-4 is a low nanomolar O-GlcNAc transferase (OGT) inhibitor, with an EC50 of 3 μM in cells.
[References]

[1] Martin SES, et al. Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors. J Am Chem Soc. 2018 Oct 24;140(42):13542-13545. DOI:10.1021/jacs.8b07328
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