| Identification | Back Directory | [Name]
FT-895) | [CAS]
2225728-57-2 | [Synonyms]
FT-895)
FT895
(FT 895
1H-Isoindole-4-carboxamide, 2,3-dihydro-N-hydroxy-1,1-dimethyl-2-[5-(trifluoromethyl)-2-pyrazinyl]- | [Molecular Formula]
C16H15F3N4O2 | [MDL Number]
MFCD31813663 | [MOL File]
2225728-57-2.mol | [Molecular Weight]
352.31 |
| Hazard Information | Back Directory | [Uses]
FT895 is a potent and selective HDAC11 inhibitor with an IC50 of 3 nM[1]. | [Biological Activity]
FT895 is a potent and selective HDAC11 inhibitor with an IC50 of 3 nM[1].
FT895 is a highly selective HDAC11 inhibitor showing greater than 1000-fold selectivity against the other 10 members of the HDAC family[1]. | [IC 50]
HDAC11: 3 nM (IC50) | [References]
[1]. Martin MW, et al. Discovery of novel N-hydroxy-2-arylisoindoline-4-carboxamides as potent and selective inhibitors of HDAC11. Bioorg Med Chem Lett. 2018 Jul 1;28(12):2143-2147. |
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| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|