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ChemicalBook--->CAS DataBase List--->22255-22-7

22255-22-7

22255-22-7 Structure

22255-22-7 Structure
IdentificationBack Directory
[Name]

3,4',5-TRIMETHOXY-TRANS-STILBENE
[CAS]

22255-22-7
[Synonyms]

TriMethoxystibene
Trimethoxystilbene
TRISMETHOXY RESVERATROL
Tri-O-methylresveratrol
Resveratrol three ether
Trimethoxy-trans-stilbene
3,5,4'-TriMethoxy Stilbene
trans-Trimethoxyresveratrol
(E)-3,5,4'-Trimethoxystilbene
trans-trismethoxy Resveratrol
E-Resveratrol TriMethyl Ether
B-0022 TrisMethoxyresveratrol
(E)-3,4',5-Trimethoxystilbene
3,5,4'-Trimethoxy-trans-stilbene
trans-3,4',5-TriMethoxy-stilbene
3,4',5-TRIMETHOXY-TRANS-STILBENE
3,4,5-TRIMETHOXY-TRANS-STILBENE 95+%
(E)-1,3-Dimethoxy-5-(4-methoxystyryl)benzene
1 (E)-5-[2-(4-HYDROXYPHENYL)ETHENYL]-1,3-BENZENE DIOL
1,3-DIMETHOXY-5-[(E)-2-(4-METHOXY-PHENYL)-VINYL]-BENZENE
1,3-DIMETHOXY-5-[(1E)-2-(4-METHOXYPHENYL)ETHENYL]-BENZENE
TRANS-1-(3,5-DIMETHOXYPHENYL)-2-(4-METHOXYPHENYL)ETHYLENE
Benzene,1,3-diMethoxy-5-[(1E)-2-(4-Methoxyphenyl)ethenyl]-
[EINECS(EC#)]

1312995-182-4
[Molecular Formula]

C17H18O3
[MDL Number]

MFCD02093500
[MOL File]

22255-22-7.mol
[Molecular Weight]

270.32
Chemical PropertiesBack Directory
[Appearance]

Pale Yellow Oil
[Melting point ]

57°C
[Boiling point ]

423.8±35.0 °C(Predicted)
[density ]

1.104±0.06 g/cm3(Predicted)
[storage temp. ]

?20°C
[solubility ]

DMSO: ≥34mg/mL
[form ]

powder to crystal
[color ]

white to tan
[CAS DataBase Reference]

22255-22-7
Hazard InformationBack Directory
[Chemical Properties]

Pale Yellow Oil
[Uses]

A resveratrol analog with a variety of pharmacology action, including anti-cancer properties, anti-allergic activity, estrogenic activity, antiangiogenic activity, and vascular-targeting activity against microtubule-destabilization
[Uses]

A resveratrol analog with a variety of pharmacology action, including inst microtubule-destabilization
[Uses]

Phenolic compounds, particularly flavonoids, from plant sources have long been observed to have antioxidant activity with potential benefits for human health. Resveratrol is a potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity. When the three phenolic hydroxyl groups of resveratrol are converted to methyl ethers, the inhibition of cell growth and pro-apoptotic activities of resveratrol are enhanced.
[Description]

trans-trismethoxy Resveratrol is a polyketide synthase-derived stilbene originally isolated from Virola cuspidata that has diverse biological activities. It is cytotoxic to several cancer cell lines, including PC3, KB, HT-29, SW480, and HL-60 cells (IC50s =3.6, 10.2, 16.1, 54, and 2.5 μM, respectively). trans-trismethoxy Resveratrol (15 μM) inhibits TNF-α-induced activation of NF-κB in HEK293T cells in a reporter assay. It inhibits angiogenesis in zebrafish embryos when used at a concentration of 0.1 μM.
[storage]

Store at -20°C
Safety DataBack Directory
[Hazard Codes ]

Xi,N
[Risk Statements ]

36/37/38-50/53-41-37/38
[Safety Statements ]

26-36/37/39-61-60-39
[RIDADR ]

UN 3077 9 / PGIII
[HS Code ]

2909.30.6000
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