| Identification | Back Directory | [Name]
6,8-DIFLUORO-7-HYDROXY-4-METHYLCOUMARIN | [CAS]
215868-23-8 | [Synonyms]
Hymecromone Impurity 5
6,8-DIFLUORO-7-HYDROXY-4-METHYLCOUMARIN
6,8-Difluoro-7-hydroxy-4-methylcoumarin (DIFMU)
6,8-Difluoro-7-hydroxy-4-methyl-2h-chromen-2-one
6,8-Difluoro-7-hydroxy-4-methyl-2H-1-benzopyran-2-one
2H-1-Benzopyran-2-one, 6,8-difluoro-7-hydroxy-4-methyl- | [Molecular Formula]
C10H6F2O3 | [MDL Number]
MFCD01073675 | [MOL File]
215868-23-8.mol | [Molecular Weight]
212.15 |
| Chemical Properties | Back Directory | [Melting point ]
213-215°C | [Boiling point ]
332.3±42.0 °C(Predicted) | [density ]
1.494±0.06 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Insoluble in water; soluble in chloroform,
N,N-dimethylformamide, dimethyl sulfoxide | [form ]
Off-White to Pale Yellow Soild | [pka]
4.7, (at 22℃)
(calcd.) 5.50 ± 0.20, most acidic, temperature:
25 °C | [color ]
Colorless needles; white solid | [λmax]
358 nm (Buffers pH 10.0, pH 9.0) | [Stability:]
Hygroscopic | [Biological Applications]
Amplifying/detectingnucleic acid sequences; analyzing peptides, sugarchains; detecting bacteria; detecting/quantifyingnucleic acids; a substrate for measuring acylprotein thioesterase (APT) activity,, α-amylaseactivity, aryl sulfatases activity, β-galactosidasesactivity,,, guanidinobenzoatase activity, β-lactamaseactivity, lipase activity, phosphatases activity,,phospholipase LYPLAL activity, protein kinasesactivity, xylanase activity; diagnosing/treatingtraumatic brain injury; treating amyloidogenic disease;as temperature sensor, | [Major Application]
Detecting/quantifying/measuring metals (beryllium, chromium, lead) |
| Hazard Information | Back Directory | [Uses]
6,8-Difluoro-7-hydroxy-4-methylcoumarin (DIFMU) was used for the diagnostic detection of natural killer cell-activity. | [Definition]
ChEBI: 6,8-difluoro-7-hydroxy-4-methylcoumarin is a hydroxycoumarin. It has a role as a fluorochrome. | [Biological Activity]
Fluorescent product of hydrolysis of fluorogenic phosphatase substrate DiFMUP.
DiFMU is a fluorescent product of hydrolysis of fluorogenic phosphatase substrate DiFMUP. DiFMU excitation wavelength is 358nm and emission can be detected at 455 nm. |
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| Company Name: |
Merck KGaA
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21-20338288 |
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www.sigmaaldrich.cn |
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Carbosynth
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+86 512 6260 5585 |
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www.carbosynth.com |
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