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ChemicalBook--->CAS DataBase List--->21215-62-3

21215-62-3

21215-62-3 Structure

21215-62-3 Structure
IdentificationBack Directory
[Name]

CALCITONIN, HUMAN
[CAS]

21215-62-3
[Synonyms]

calcitonin M
Unii-I0io929019
Einecs 244-276-2
human C carcinoma
CALCITONIN, HUMAN
hCT Thyrocalcitonin
CALCITONIN M, HUMAN*
THYROCALCITONIN HUMAN
Human calcitonin (1-32)
Calcitonin, human synthetic
1,7-Dicarbacalcitonin【human】
Calcitonin Human,recombinant
Calcitonin,huMan,Calcitonin,hu
Calcitonin, human, for bioassay
calcitonin m, human c carcinoma
Calcitonin, human reduced cyclic(1→7)-disulfide
CGNLSTCMLGTYTQDFNKFHTFPQTAIGVGAP-NH2 (DISULFIDE BRIDGE: 1-7)
Calcitonin M, human C carcinoma, Calcitonin, human reduced cyclic (1-7)-disulfide, hCT, Thyrocalcitonin
CYS-GLY-ASN-LEU-SER-THR-CYS-MET-LEU-GLY-THR-TYR-THR-GLN-ASP-PHE-ASN-LYS-PHE-HIS-THR-PHE-PRO-GLN-THR-ALA-ILE-GLY-VAL-GLY-ALA-PRO-NH2
CYST-GLY-ASN-LEU-SER-THR-CYST-MET-LEU-GLY-THR-TYR-THR-GLN-AS-PHE-ASN-LYS-PHE-HIS-THR-PHE-PRO-GLN-THR-ALA-ILE-GLY-VAL-GLY-ALA-PRO NH2
H-CYS-GLY-ASN-LEU-SER-THR-CYS-MET-LEU-GLY-THR-TYR-THR-GLN-ASP-PHE-ASN-LYS-PHE-HIS-THR-PHE-PRO-GLN-THR-ALA-ILE-GLY-VAL-GLY-ALA-PRO-NH2
CYS-GLY-ASN-LEU-SER-THR-CYS-MET-LEU-GLY-THR-TYR-THR-GLN-ASP-PHE-ASN-LYS-PHE-HIS-THR-PHE-PRO-GLN-THR-ALA-ILE-GLY-VAL-GLY-ALA-PRO-NH2 HUMAN
H-CYS-GLY-ASN-LEU-SER-THR-CYS-MET-LEU-GLY-THR-TYR-THR-GLN-ASP-PHE-ASN-LYS-PHE-HIS-THR-PHE-PRO-GLN-THR-ALA-ILE-GLY-VAL-GLY-ALA-PRO-NH2 (DISULFIDE BRIDGE: 1-7)
[EINECS(EC#)]

244-276-2
[Molecular Formula]

C151H226N40O45S3
[MDL Number]

MFCD00167520
[MOL File]

21215-62-3.mol
[Molecular Weight]

3417.85
Chemical PropertiesBack Directory
[Boiling point ]

3061.8±65.0 °C(Predicted)
[density ]

1.326±0.06 g/cm3(Predicted)
[RTECS ]

XP3560000
[storage temp. ]

−20°C
[solubility ]

Soluble in DMSO
[form ]

powder
[color ]

White to off-white
[biological source]

synthetic (organic)
[Water Solubility ]

Soluble to 2 mg/ml in water
[Merck ]

13,1642
Safety DataBack Directory
[Safety Statements ]

22-24/25
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Calcitonin human has been used to study its ability to stimulate cAMP production post transfection in mammalian cell by activating human CALCRL (calcitonin receptor like receptor gene)- receptor activity-modifying protein 1 (RAMP1) and CTR (calcitonin receptor).
[Uses]

Decreases blood calcium and phosphate due to inhibition of resorption by osteoblasts and osteocytes. A carrier peptide that can be used to internalize fusion proteins
[Uses]

Regulator (calcium).
[Brand name]

Calcimar (Rhone- Poulenc Rorer);.
[Biochem/physiol Actions]

Calcitonin, also referred to as thyrocalcitonin, is a 32 amino acid peptide hormone, which is present abundantly in seminal plasma compared to serum. It acts as a first messenger and hence regulates the the production of cAMP as well as mammalian sperm function. It also facilitates the regulation of different isoforms of adenylyl cyclase.
[storage]

Store at -20°C
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